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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KCNB1 All Species: 15.15
Human Site: S720 Identified Species: 47.62
UniProt: Q14721 Number Species: 7
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14721 NP_004966.1 858 95878 S720 L L D K A V L S P E S S I Y T
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_543042 858 96045 S720 L L D R P V L S P E S S I Y T
Cat Felis silvestris
Mouse Mus musculus Q03717 857 95674 S719 L L D K P V L S P E S S I Y T
Rat Rattus norvegicus P15387 857 95619 S719 L L D K P V L S P E S S I Y T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507252 997 108259 P657 A R R G K S V P G Y I D A D T
Chicken Gallus gallus
Frog Xenopus laevis NP_001079257 876 99069 R737 L Y T T A S A R T P S K S P E
Zebra Danio Brachydanio rerio XP_682848 827 92522 S690 S G G P L S D S S I L S D H S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001195169 1105 121957 T917 S G P V P M Q T I T S A E D A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 97.4 N.A. 93.4 94 N.A. 53.7 N.A. 75.5 66.6 N.A. N.A. N.A. N.A. 38.3
Protein Similarity: 100 N.A. N.A. 98.5 N.A. 96.3 96.1 N.A. 60.5 N.A. 85 77.3 N.A. N.A. N.A. N.A. 52.9
P-Site Identity: 100 N.A. N.A. 86.6 N.A. 93.3 93.3 N.A. 6.6 N.A. 20 13.3 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 N.A. N.A. 93.3 N.A. 93.3 93.3 N.A. 13.3 N.A. 20 26.6 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 0 0 0 25 0 13 0 0 0 0 13 13 0 13 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 50 0 0 0 13 0 0 0 0 13 13 25 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 50 0 0 13 0 13 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 25 13 13 0 0 0 0 13 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 13 0 % H
% Ile: 0 0 0 0 0 0 0 0 13 13 13 0 50 0 0 % I
% Lys: 0 0 0 38 13 0 0 0 0 0 0 13 0 0 0 % K
% Leu: 63 50 0 0 13 0 50 0 0 0 13 0 0 0 0 % L
% Met: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 13 13 50 0 0 13 50 13 0 0 0 13 0 % P
% Gln: 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % Q
% Arg: 0 13 13 13 0 0 0 13 0 0 0 0 0 0 0 % R
% Ser: 25 0 0 0 0 38 0 63 13 0 75 63 13 0 13 % S
% Thr: 0 0 13 13 0 0 0 13 13 13 0 0 0 0 63 % T
% Val: 0 0 0 13 0 50 13 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 13 0 0 0 0 0 0 0 13 0 0 0 50 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _